Submitted by: sdemir   Date: 2011-12-04 20:35
ADAPTIVE IMMUNITY
Dr. Gary Kaiser

Link için tıklayınız

TABLE OF CONTENTS

TOPICS

I. INTRODUCTION
A. Overview of Adaptive Immunity

B. Major Cells and Key Cell Surface Molecules Involved in the Immune Responses

1. MHC Molecules

2. Antigen-Presenting Cells (APCs)

3. B-Lymphocytes (B-Cells)

4. T4-Lymphocytes (T4-Cells)

5. Th1,Th2, and Th17 Cells

6. Regulatory T-Lymphocytes (T-reg Cells)

7. T8-Lymphocytes (T8-Cells)

8. Natural Killer T- Lymphocytes (NK cells)

9. Natural Killer Cells (NK Cells)

C. The Lymphoid System

D. An Overview of the Steps Involved in Adaptive Immune Responses

II. HUMORAL IMMUNITY
A. Antibodies (Immunoglobulins)

1. An Overview

2. Antibody Structure

3. The 5 Classes (Isotypes) of Human Antibodies

4. Generation of Antibody Diversity

5. Clonal Selection and Clonal Expansion

6. The Steps Involved in Antibody Production

7. Anamnestic (Memory) Response

B. Ways That Antibodies Help to Defend the Body

1. An Overview

2. Opsonization

3. Cytolysis by the Membrane Attack Complex (MAC)

4. Antibody-dependent Cellular Cytotoxicity (ADCC) by NK Cells

5. Neutralization of Exotoxins

6. Neutralization of Viruses

7. Preventing Bacterial Adherence

8. Agglutination of Microorganisms

9. Immobilization of Bacteria and Protozoans

C. Naturally and Artificially Acquired Active and Passive Immunity

1. Naturally Acquired Immunity

2. Artificially Acquired Immunity

D. Monoclonal Antibodies

III. CELL-MEDIATED IMMUNITY
A. Cell-Mediated Immunity: An Overview

B. The Steps Involved in Cell-Mediated Immunity

C. Ways That Cell-Mediated Immunity Help to Defend the Body

1. Activating Antigen-Specific Cytotoxic T- Lymphocytes (CTLs)

2. Activating Macrophages and NK Cells

3. Stimulating Cells to Secrete Cytokines

D. Active and Passive Immunotherapy to Stimulate Cell-Mediated Immunity against Tumors

IV. IMMUNODEFICIENCY
A. An Overview
B. Primary Immunodeficiency
C. Secondary Immunodeficiency
V. HYPERSENSITIVITIES
A. An Overview

B. Immediate Hypersensitivities

1. Type I

2. Type II

3. Type III

4. Type V

C. Delayed Hypersensitivities (Type IV)

D. Superantigens

Comments: (0)

Henüz yorum yapılmamış