Clinical Infectious Diseases 1999; 29:745–58
Symptomatic urinary tract infections (UTIs) are among the most common of bacterial infections. Their magnitude can be judged either by visits to physicians, estimated as high as 8,000,000 per year in the United States (mostly for cystitis), or by admission to hospitals, estimated at 100,000 per year (mostly for acute pyelonephritis). A variety of antimicrobial regimens comprising different drugs, doses, schedules, and durations have been used to treat UTIs. Thus, the Infectious Diseases Society of America (IDSA) convened a committee to systematically review this topic and develop guidelines for the antimicrobial treatment of acute uncomplicated bacterial cystitis and acute pyelonephritis in women.
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