Antinuclear Antibody (ANA) Testing for Connective Tissue Disease



This guideline describes appropriate use of antinuclear antibody (ANA) testing (fee item 90280) in the diagnosis of connective tissue disease (CTD), also referred to as “systemic rheumatic disease”. It applies only to individuals 17 years of age and over. The guideline does not address ANA testing in the investigation of unexplained infertility, adverse pregnancy outcomes, liver disease or thrombotic disorders.

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