Liver Chemistry Abnormalities in Adults – Evaluation and Interpretation



This guideline provides recommendations for the interpretation and evaluation of abnormal liver test results in adults. It should be used in conjunction with other guidelines, such as Clinical Management of Chronic Hepatitis B, Clinical Management of Chronic Hepatitis C, Investigation and Management of Iron Overload and Viral Hepatitis Testing.

Abnormal liver tests may indicate an abnormality of the liver and provide clues as to the nature of the problem. However, in an asymptomatic patient, mild abnormalities may not be clinically significant. A systematic approach to evaluating the patient and ordering further tests will help to efficiently identify any underlying disease. Further testing and referrals may not be necessary in many circumstances.

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